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Pinnacle Research Labs

Topical: RU58841 + Minoxidil

Topical: RU58841 + Minoxidil

$99.95 AUD
$99.95 AUD
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Store in fridge for longer shelf life and shake well before use

Studied for its role in: 

  • Investigated as a non-steroidal androgen receptor antagonist, with research exploring its ability to inhibit androgen receptor activation within hair follicles.
  • Studied for its potential to modulate androgen signaling in scalp tissue, particularly in experimental models of androgen-dependent hair follicle biology.
  • Research explores its effects on hair follicle cycling and maintenance, with investigations focused on localized androgen receptor inhibition.
  • Investigated for its influence on hair follicle miniaturization pathways, with preclinical studies examining mechanisms involved in follicular health.
  • Studied for its potential to support hair follicle function by reducing androgen-mediated signaling in laboratory research.
  • Research continues to evaluate its pharmacological activity and androgen receptor interactions in preclinical models of scalp biology.

Product Description

*Please store product in fridge and apply 25-35 minutes post shower.

RU58841 and Minoxidil are both compounds used in the treatment of hair loss, but they work through different mechanisms:

RU58841: A topical anti-androgen that blocks DHT (dihydrotestosterone) receptors in the scalp, preventing DHT from binding to hair follicles, which is a key factor in androgenic alopecia (male and female pattern baldness). It helps reduce hair follicle miniaturization and promotes hair growth.

Minoxidil: A vasodilator that increases blood flow to the scalp, stimulating hair follicles and promoting hair growth. Its exact mechanism isn’t fully understood, but it’s believed to extend the anagen (growth) phase of hair follicles and increase follicle size.

Both are effective for promoting hair regrowth but target different aspects of hair loss: RU58841 targets hormonal factors, while Minoxidil improves scalp circulation and follicle health.

How it works

RU58841 is a topical anti-androgen that selectively inhibits the binding of dihydrotestosterone (DHT) to androgen receptors on hair follicle cells. By blocking DHT at the receptor level, it prevents DHT-mediated follicular miniaturization and prolongs the anagen (growth) phase of hair follicles, mitigating androgenic alopecia.

Minoxidil, a potassium channel opener, enhances vasodilation and increases blood flow to the scalp, leading to improved oxygen, nutrient, and growth factor delivery to hair follicles. It stimulates prolongation of the anagen phase and induces follicular regeneration, likely via activation of VEGF and PDGF pathways, although its exact mechanism remains incompletely understood.

COA (Certificate of analysis)

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Legal Disclaimer

Disclaimer: All products are sold for research purposes only. The available products are not intended for human consumption, personal use, or any form of medical application. These materials are strictly for laboratory research, scientific studies, and educational purposes only (e.g.., lab or university use). Pinnacle Research Labs is not a licensed pharmacy, medical facility, or compounding service, and does not offer products for medical or clinical applications. Pinnacle Research Labs has never and will never make health and/or therapeutic claims. Buy purchasing our products you are agreeing to our terms of services.

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