Topical: Minoxidil

Minoxidil is a vasodilator that, when applied topically to the scalp, enhances blood circulation to hair follicles. It stimulates hair growth by extending the anagen (growth) phase of hair follicles and increasing follicle size. Although its exact mechanism is not fully understood, it's believed to promote follicular regeneration through the activation of growth factors like VEGF and PDGF, improving hair density and thickness in conditions like androgenic alopecia.

Minoxidil works by opening potassium channels in the cell membranes of hair follicle cells, leading to vasodilation and increased blood flow to the scalp. This enhanced circulation improves the delivery of oxygen, nutrients, and growth factors to hair follicles. Minoxidil is believed to promote follicular regeneration by prolonging the anagen phase, increasing follicle size, and potentially activating pathways like VEGF and PDGF, which support hair growth and follicle health.

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